15. Shin, I.; Wang, Y.; Liu, A.* A new regime of the histidyl-ligated heme-dependent oxygenase superfamily. Proc. Natl. Acad. Sci. U. S. A. 2021, 118(43), e2106561118 (DOI: 10.1073/pnas.2106561118)  

14. Wang, Y.; Shin, I.; Li, J.; Liu, A.* Crystal Structure of Human Cysteamine Dioxygenase Provides a Structural Rationale for its Function as an Oxygen Sensor. J. Biol. Chem2021, 297(4), 101176 (DOI: 10.1016/j.jbc.2021.101176

13. Wang, Y.; Davis, I.; Liu, A.* Molecular rationale for partitioning between C-H and C-F bond activation in heme-dependent tyrosine hydroxylase. J. Am. Chem. Soc2021, 143(12), 4680-4693 (DOI: 10.1021/jacs.1c00175)

12. Shin, I.; Davis, I.; Nieves-Merced, K.; Wang, Y.; McHardy, S.; Liu, A.*  A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis-His ligand set revealed by the spectroscopic and structural study. Chem. Sci2021, 12(11), 3984-3998 (DOI: 10.1039/D0SC06369J)

11. Wang, Y.✝︎; Liu, KF.✝︎; Yang, Y.; Davis, I.; Liu, A.* Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc. Natl. Acad. Sci. U. S. A. 2020, 117(33), 19720-19730. (DOI: 10.1073/pnas.2005327117) 

10. Wang, Y.; Davis, I.; Yang, Y.; Davis, I.; Chen, Y.; Naik, S.; Griffith, W.; Liu, A.* Characterization of the non-heme iron center of cysteamine dioxygenase and its interaction with substrates. J. Biol. Chem2020, 295(33), 11789-11802. (DOI: 10.1074/jbc.RA120.013915)

9. Wang, Y.; Liu, A.* Carbon-fluorine bond cleavage mediated by metalloenzymes. Chem. Soc. Rev. 2020, 49, 4906-4925. (DOI: 10.1039/C9CS00740G) 

8. Nguyen, R.; Yang, Y.; Wang, Y.; Davis, I.; Liu, A.* Substrate-assisted hydroxylation and O-demethylation in the peroxidase-like cytochrome P450 enzyme CYP121. ACS Catal. 2020, 10(2), 1628-1639. (DOI: 10.1021/acscatal.9b04596)

7. Wang, Y.; Davis, I.; Shin, I.; Wherritt, D.; Griffith, W.; Dornevil, K.; Colabroy, K.; Liu, A.* Biocatalytic carbon-hydrogen and carbon-fluorine bond cleavage through hydroxylation promoted by a histidyl-ligated heme enzyme. ACS Catal. 2019, 9(6), 4764-4776. (DOI: 10.1021/acscatal.9b00231)
Featured by ACS Editors’ Choice and ACS LiveSlides

6. Wang, Y.; Shin, I.; Fu, Y.; Colabroy, K.; Liu, A.* Crystal structures of L-DOPA dioxygenase from Streptomyces Sclerotialus. Biochemistry. 2019, 58(52), 5339-5350. DOI: 10.1021/acs.biochem.9b00396)
Invited original contribution for a special issue “Current Topics in Mechanistic Enzymology 2019”

5. Wang, Y.; Griffith, W.; Li, J.; Koto, T.; Wherritt, D.; Fritz, E.; Liu, A.* Cofactor biogenesis in cysteamine dioxygenase: C-F bond cleavage with genetically incorporated unnatural tyrosine. Angew. Chem. Int. Ed. 2018, 57(27), 8149-8153. (DOI: 10.1002/ange.201803907)

​4. Li, J.; Griffith, W.; Davis, I.; Shin, I.; Wang, J.; Li, F.; Wang, Y.; Wherritt, D.; Liu, A.* Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol. 2018, 14(9), 853-860. (DOI: 10.1038/s41589-018-0085-5)

3. Wang, Y.; Li, J.; Liu, A.* Oxygen activation by mononuclear nonheme iron dioxygenases involved in the degradation of aromatics. J. Biol. Inorg. Chem. 2017, 22(2), 395-405. (DOI: 10.1007/s00775-017-1436-5)
Invited article for a special issue “60 Years of Oxygen Activation”

2. Yang, Y.; Davis, I.; Ha, U.; Wang, Y.; Shin, I.; Liu, A.* A pitcher-and-catcher mechanism drives endogenous substrate isomerization by a dehydrogenase in kynurenine metabolism. J. Biol. Chem2016, 291(51), 26252-26261. (DOI: 10.1074/jbc.M116.759712)
Featured as "Papers of the Week”

1. Zuo, B.; Liu, Y.; Wang, L.; Zhu, Y.; Wang, Y.; Wang, X.* Depth profile of the segmental dynamics at a poly(methyl methacrylate) film surface. Soft Matter, 2013,9, 9376-9384. (DOI: 10.1039/C3SM51658J)

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