The Adams Lab is part of the Department of Biochemistry and Molecular Biology at the University of Georgia. The laboratory is housed the Life Sciences building on South campus and has been in operation for nearly two decades. The group has a general interest in anaerobic microorganisms, and particularly those growing near and above 100°C, the so-called hyperthermophiles. The archaeon Pyrococcus furiosus and the bacterium Caldicellulosiruptor bescii are being used as model systems for various research projects. Projects involve the physiology, metabolism, enzymology, metal utilization and the metabolic and genetic engineering of these organisms. For example, we have demonstrated that P. furiosus can be engineered to produce lactate, a metabolite that it does not make naturally.