HOW DO CELLS BUILD CILIA?

We seek one graduate student to join the lab in fall 2020. Inquire about rotations (lechtrek@uga.edu).

Postdoctoral position available. Inquiries to lechtrek@uga.edu


2020

The big farewell !

jin daijin dai

jin dai

Peiwei Liu, Kewei Yu, and Jenna Wingfield move on to new missions!


Karl Lechtreck presents at the 8th UK Cilia eSymposium

jin daijin dai

Go, Pleasantine, go!


Our Spring graduates Kewei Yu and Jenna Wingfield

jin daijin dai

jin daijin dai


First lab meeting by Zoom

ragdsrthncvnd

Peiwei reports on the assembly of PKD2 compartments in cilia


Congratulations Master Kewei Yu and Doctor Jenna L. Wingfield!

fghjsafahtryjh 

Kewei and Jenna defended on April 8 and April 10, respectively, via Zoom in times of Covid19.


jhiukfvbuyvguk

Accepted for publication in the JCB!

Liu, P., Lou, X., Wingfield, J.L., Lin, J., Nicastro, D. and Lechtreck, K.-F. (2020) 

Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia.


Happy 2020 for the Lechtreck lab. May your wildest dreams come true.

dai


2019

Fall 2019 - Farewell dinner for Ilaria Mengoni

jinjinjin


Cell-a-bration Barrow Elementary School 2019

 jin jin (drawings from student notebook)

gif videojin

jinjin

jingif video

jingif video


Students impress at FASEB Cilia meeting in Snowmass, Colorado - August 4 - 9, 2019.

jinjin

jinjin

(from top left): Jenna Wingfield discussing her poster on IFT turnaround at the tip with Anthony Roberts (UK), Peiwei Liu presenting his data on polycystin-2, Jin Dai giving his paper Arl13, and Kewei Yu with Susan Dutcher (WashU) at her poster on flagellar asymmetry. Peiwei Liu, Jenna Wingfield, and Kewei Yu received awards for their presentations.

jin


Celebrating 50 years Apollo 11 (not Area 51)

jin

from left: Kewei Yu (Enterprise), Jenna Wingfield (Saturn 5), Jin Dai (Stormtrooper), Ilaria Mengoni (Moon), Karl Lechtreck (E.T.), and Peiwei Liu (Eagle) in our microscope room


Summer lab party

jin


Master Dipna and family

jinMay 10, 2019

Dipna Venkatachalam graduates.


Shannon graduates!

jin

After four years of golden service to the lab Shannon Freeland will move on to Mercer University School of Medicine.


Congratulations Dipna!

jinjinjin

Dipna Venkatachalam completed her MS on April 18, 2019.


February 13, 2019:  Our NIH proposal "Regulation of protein transport in cilia" was renewed! 

gif


jinjin

Come drive with us: Chlamydomonas - the Mercedes among the cilia models. 


2018

jinjin

Merry Christmas from the Lechtreck lab


ASCB/EMBO meeting 2018 San Diego

jinjinjin

jinpicturejin

Karl Lechtreck gave a paper in the CILIA SIGNALING special interest subgroup; Jenna Wingfield presented a poster.


CBIO3400 end-of-class party

jinjin

Julie Stanton and Karl Lechtreck presenting the "THE CELL" cake and the students of CBIO3400.


Cell-a-Bration at Barrow Elementary School

jinjin

jingif video

jin gif video jin

jingif video

jinjin

The Barrow Fifth Graders with Dr. Ilaria Mengoni, James Anderson, Dr. Karl Lechtreck, Manashree Malpe, and Dr. Yuyang Jiang. And the Creepy Crawlers (aka protists) from UGA's turtle pond.


Visit to Dove Creek Elementary School

blubjin

jinjin

Dove Creek Fifth Graders with Dr. Ilaria Mengoni, Jin Dai, and Jenna Wingfield


We welcome Kewei Yu for her rotation in the lab.

image

 

 

 

 

 

 

 

Kewei Yu

Master's student

Department of Cellular Biology

 

 

 

 


Jin Dai's paper on outer dynein arm transport published in MBoC.  Congratulations!

jin

jinvideo3

Dai, J., Barbieri, F., Mitchell, D.R., and Lechtreck, K.-F. (2018). In vivo analysis of outer arm dynein transport reveals cargo-specific IFT properties. Mol. Biol. Cell Aug 22:mbcE18050291.


Our study on radial spoke assembly is published!

gif videogif video

In vivo analyses of radial spoke transport, assembly, repair and maintenance radial spoke transport (2018). by Karl F. Lechtreck, Ilaria Mengoni, Batare Okivie, and Kiersten B. Hilderhoff. Cytoskeleton August 1.


18th INTERNATIONAL CONFERENCE ON THE CELL AND MOLECULAR BIOLOGY OF CHLAMYDOMONAS, Washington DC, June 17 - 21, 2018

Chlamy meeting

imgbbbb

Jin Dai and Peiwei Liu presented posters, Karl Lechtreck gave a paper at Chlamy2018.


Karl Lechtreck visits Tianjin University of Science and Technology (TEDA) and Tsinghua University (Beijing)

img

tsingua

tsinghua


Farewell for Aaron and Penny

party

party


At the Potter-Convention

many

monitor


Congratulations to Dr. Harris and Dr. Louka !

ab

Aaron Harris and Panagiota "Penny" Louka (Gaertig lab) successfully defended their theses on Mar 26 and Apr 6. 


Gehrig and Kiersten moving on.

Image removed.

After spending several terms as undergraduate researchers in the lab working on Chlamydomonas mutants, Gehrig Broxton and Kiersten Hilderhoff will graduate soon.


After 3 long years, our study on radial spoke assembly nears completion.

gif video

Live image of mCherry-RSP3 RSP-sfGFP chimeric zygotes obtained by mating 

 gif video

Dr. Mengoni using balloon "Chlamys" to explain the generation of 2-color chimeras


Happy New Year!  

Image removed.

Up to an icy start - temperatures in the microcope room fluctuate by up to 9 C! Main water pipe to science hill broke. Thank you President Trump for stopping global warming! Such a big button. The president appearently suffers from LMS (Liddle Man syndrome).  I can tell because I'm affected myself.  Karl


2017

December 22: It's proceeding!

jinjin

Peiwei Liu's paper on BBSome-dependent protein transport has been accepted in PNAS. Congratulations!


November 3:  Cell-a-bration at Barrow Elementary School

jinjin

jin

jin

jin

jinjin

 

 


Dipna Venkatachalam, Jenna Wingfield, Ilaria Mengoni, Aaron Harris and Karl Lechtreck visited Barrow School for hands-on science and microscopy classes for 5th graders. Once a Barrow Buddy, always a Barrow Buddy!


Image removed. Evening sun on the BioSci Bldg roof.


August 21, 2017 - the path of totality.

Image removed.Image removed.Image removed.

 

FASEB Science Research Conference "Biology of Cilia and Flagella"

                                 "Absence of evidence is not evidence of absence"

Image removed.Image removed.

Image removed.

Image removed.Image removed.

Dipna Venkatachalam, Peiwei Liu, Jenna Wingfield, and Karl Lechtreck presented posters and papers at the FASEB meeting in Scottsdale Arizona.  Images were taken in the McDowell Sonoran Preserve and the new Scottsdale OdySea Aquarium. Karl will co-organize the FASEB meetings in 2019 and 2011.

SEER Award for Jenna Wingfield

Image removed.Image removed.

for her PechaKucha-style presentation on faculty professional training and its application in STEM education - awarded by UGA's 'Scientists Engaged in Education Research (SEER)'.

 

Karl Lechtreck is tenured!

Image removed.Image removed.

with Provost  Pamella Whitten and President Jere Morehead at UGA's PnT reception, May 2017.

5/16/2017:  Jenna Wingfield's paper accepted in eLIFE!

Image removed.

"IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium"

Aaron Harris - 2017 Teaching Award

Image removed.Image removed.

and some sweet rewards from the CBIO3400 class in form of '9+2', '9+0', and 'microtubular transport' cupcakes.

Gehrig Broxton presents at the CURO symposium

Image removed.

Gehrig presenting his poster on an OFD1 mutant in Chlamydomonas to Dr. Mark Farmer.

 

Farewell for Francesco

Image removed. 

Francesco Barbieri from Università degli studi di Siena returns home in March. But not before a nice glass of green algae.

 

Warhol's Axonemes

Image removed.

By Jenna Wingfield, Franklin College of Arts and Sciences, Ph.D Student, Cellular Biology

 

Visitors from UWG

Image removed.

Kevin Nguyen, DaliDavis, Ja'Von Swint from University of Western Georgia visited the lab on March 20/21.  

Fresh from the Graduate School:  Our own Aaron Harris received the 2017 Graduate School Excellence in Teaching Award! Congrats!

Image removed.

Spring brake lunch @ Pulaski Heights BBQ 

Image removed.

Image removed.

Pulaski BBQ offers an inspiring backdrop for IFT train research.  And they do smoked tofu and kimshi.

 

Visit to Mautusi Mitra (University of West Georgia)

Image removed. Image removed.

Dinner with the Mitra lab.   Collection of mostly Georgian fish at UWG.

2016

Happy Holidays

Image removed.

It's a laboratory Christmas with Jenna Wingfield's amazing model organism ornaments. 

Francesco Barbieri visits lab

Image removed.Image removed.

We wecome Francesco Barbieri, a visiting Ph.D. student fromthe Lupetti laboratory at the Università degli studi di Siena, Italy.  Francesco will work on cargo transport by IFT trains using a combination of TIRF imaging and electron microscopy. The kymograms document the fixation of an IFT train (IFT20-mCherry, red) while transporting an outer dyein arm (IC2-NG, green).

Jenna Wingfield wins the poster presentation award at the Chlamydomonas 2016 meeting, Kyoto, Japan !

Image removed.Image removed.

Image removed.Image removed.

Karl Lechtreck presented data on outer dynein arm transport in flagella and chaired session No. 8 and Jenna Wingfield presented her prize-winning poster at the 17th International Conference on the Cell and Molecular Biology of Chlamydomonas (69th Yamada Conference) in Kyoto, Japan.

The lab's end of term party

Image removed.Image removed.

at Karl's place

Image removed.Image removed.

Shannon Freeland - our very best student worker !

Image removed.

Shannon Freeland, student worker in the lab, and Karl Lechtreck at the Student Employee of the Year Awards Luncheon

Chlamydomonas Resource Center new web site

Image removed.

Our photo of stained Chlamydomonas zygotes has been chosen as a banner of the new Chlamydomonas Resource Center website (http://www.chlamycollection.org/). 

Happy 2016! May the Force be with you. And may the odds be ever in your favor.

Image removed.(seen at JJ's fleamarket)

2015

Dec 18, 2015: The one and only Julie M. Craft graduates. Congrats doctor!

Image removed.Image removed.Image removed.

Happy Holidays !

Image removed.Image removed.Image removed.

Fungal Christmas tree: Top: Taloromyces stipitatus, tree: Aspergillus nidulans, ornaments: Penicillium marneffei, trunk: Aspergillus terreus.  

Fungal snowman: hat, eyes, mouth, buttons: Aspergillus niger; arms: Aspergillus nidulans; nose: Aspergillus terreus with Penicillium marneffei; body: Neosartorya fischeri.

Source: blogs.jcvi.org.

 

Aaron Harris' paper on EB1 in cilia accepted for Mol. Biol. Cell !  Congratulations !

and presented his work at the 2015 ASCB meeting in San Diego ! 

Image removed.Image removed.

EB1-mNeonGreen comets in C. reinhardtii revealing the dynamics of cell body microtubules (click on image).

 

Review on cargo transport by IFT published in TIBS.

Image removed.

"The Omnipresent Cilium - Structure, Signalling, and Motion"

Image removed.(click to watch video)

Karl Lechtreck gives a paper at the 5th International caesar Conference on cilia.

Cell-A-bration

Image removed.Image removed.

Image removed.Image removed.

September 25: visiting Barrow Elementary School for science classes

Celebrating US-Mexican Friendship

Image removed.

Welcome to our new lab member Ilaria Mengoni PhD

           Image removed.

Dr. Ilaria Mengoni joined the lab on July 27.  Ilaria received her PhD from the University of Bologna studying the role of Apolipoprotein E in brain function.

High in the mountains: FASEB conference on the "Biology of Cilia and Flagella" July 19-24, Snowmass, CO.

Image removed.Image removed.

Most lab members (Julie Craft, Aaron Harris, Karl Lechtreck, and Peiwei Liu) participated in the FASEB conference; Karl Lechtreck presented a summary of the labs research, Julie Craft and Aaron Harris presented posters.

Riding the IFT train: White water rafting on the Colorado River.

 

June 22: Batare Okivie moves on.

Image removed.Image removed.

After a year in the lab, Batare Okivie leaves for Drexel Univesity, College of Medicine, pre-medical program, Philadephia. But not before having a farewell party and beiing celebrated for excellent lab work.  Her pet project, assembly and transport of radial spokes, will be taken over by Karl Lechtreck and Dr. Ilaria Mengoni. 

Lab-outing to the UGA Marine Institut, Sapelo Island, GA (May 6-8)

Image removed.Image removed.

Image removed.Image removed.

Image removed.Image removed.

Together with the Gaertig lab (Jacek Gaertig, Mayukh Guha, Yuyang 'Patrick' Jiang, Panagiotta Louka) and students from the Eggenschwiler lab (Ashley Snouffer, Jonathon Walsh)

we visited the UGA Marine Institute on Sapelo Island for a 3-day science retreat.  Presentations by graduate studetns, postdocs,and technicians were mixed with beach time, bike rides, and cooking.

 

Gordon Research Conference on Cilia, Mucus, and Mucociliary Interactions

Image removed.

Just published:

Image removed.Image removed.

Craft, J.M., Harris, J.A., Hyman, S., Kner, P., and Lechtreck, K.-F. (2015). Tubulin Transport by IFT is Upregulated during Ciliary Growth by a Cilium-autonomous Mechanism. J. Cell Biol. 208:223-37

The work will be highlighted by a JCB biosights video on January 19, 2015.

2014

Great news: Julie Craft's paper on tubulin transport has been accepted by the Journal of Cell Biology.

Julie Craft and Aaron Harris presented their work on tubulin transport at this years ASCB meeting in Philadelphia.

Image removed.Image removed. 

Karl Lechtreck presented at CILIA2014 in Paris.

Image removed.Image removed.

 

Sebastian Hyman heads of to Mercer University School of Medicine

Image removed.Image removed.

Image removed.Image removed.

(after handing the golden pipette over to Batare Okivie, receiving his reward, possing one last time with his Joels. Gone but not forgotten.)

16th International Conference on the Cell and Molecular Biology of Chlamydomonas, June 8 - 13, 2014, Asilomar CA

Image removed.

Image removed.

Julie Craft presenting her work on tubulin transport in flagella

Image removed.Image removed.Image removed.

Welcome to our summer students

Image removed.Image removed.

Heather Bomberger (Virginia Tech) and Aachi Kalra (Northview High School, Johns Creek, GA) spend the summer in the lab on research interships. 

Heather Bomberger, a sophomore in Biological Systems Engineering and minoring in Scieneering, participates in the NSF-sponsored REU program “Interdisciplinary Research Experience of Nanotechnology and Biomedicine” at UGA. Her project "Quantitative Analysis of Intraflagellar Protein Transport” is co-mentored by Dr. Peter Kner from UGA's College of Engineering.

Aachi Kalra participates in UGA's Young Dawgs programm, a high school internship program designed to prepare high-achieving high school juniors and seniors for post-secondary education and future careers in their areas of interest.  Aachi Kalra is interested in biomedicine; during her intership she will rescue the ift54-1 mutant using a GFP-tagged IFT54 transgene.

 

Congratulations !

Image removed.Image removed.

Fiona Bell and Deep Patel, the first undergraduates to join the lab in 2012, have graduated.

 

2013

Image removed.Image removed.

Our lab in the 6th floor annex of the Biological Science Building, built in a former green house.